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Bulletin of biotechnology

scientific journal

Construction of an antimicrobial peptide

УДК 543.645.6

Authors:

Tikhonov S.L.,

Tikhonova N.V.

Summary. A new antimicrobial peptide has been created based on the existing natural peptide. A native peptide with the following amino acid sequence PAFAASSKA was used as an object of research. The total hydrophobic ratio determined by APD = 50%. the charge is + 1, the hydrophobicity of the peptide according to Wimley-White is 1.38. The molecular weight of the input peptide is 936.029. According to the APD database, a new antimicrobial peptide has been created based on the known peptide with the following sequence: PDPAKTAPKKGSKKAVTKA, which is closest to the known AMP AP00338.

Keywords: databases, antimicrobial peptide, construction, amino acid sequence, molecular weight

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